Is CLUES a Wordle Word?

Yes. CLUES is a valid Wordle word.

It is not on the Wordle answer list, so it is unlikely to be a daily answer.

Plurals ending in S are almost never chosen as Wordle answers.

What does CLUES mean?

/kluːz/

A strand of yarn etc. as used to guide one through a labyrinth; something which points the way, a guide.
Information which may lead one to a certain point or conclusion.
An object or a kind of indication which may be used as evidence.

1 more noun definition

Insight or understanding ("to have a clue [about]" or "to have clue". See have a clue, clue stick)

To provide with a clue.“The crossword compiler wasn't sure how to clue the word "should".”
To provide someone with information which he or she lacks (often used with "in" or "up").“Smith, clue Jones in on what's been happening.”

Definition from Wiktionary, available under the CC BY-SA license.

Starter word rating: AverageIn the top 19% of all valid Wordle words for testing common letters.
Vowels: U, E
Unique letters: 5 of 5
Common letters: L, E

Hard-mode trap: 6 valid words fit the pattern _LUES. If you reach it, you may need several guesses to find the last letter.

Letter ratings use how often each letter appears in Wordle answers.

Tap its tiles to the colours Wordle showed, and the Wordle Solver lists every word that still fits, with the best next guess.