Is GUACO a Wordle Word?

Yes. GUACO is a valid Wordle word.

It is not on the Wordle answer list, so it is unlikely to be a daily answer.

What does GUACO mean?

Any of various vine-like climbing plants of Central and South America and the West Indies, including Mikania and Aristolochia species, reputed to have curative powers.

Definition from Wiktionary, available under the CC BY-SA license.

Starter word rating: WeakIn the top 48% of all valid Wordle words for testing common letters.
Vowels: U, A, O
Unique letters: 5 of 5
Common letters: A, O

Letter ratings use how often each letter appears in Wordle answers.

Tap its tiles to the colours Wordle showed, and the Wordle Solver lists every word that still fits, with the best next guess.