Is LYRES a Wordle Word?

Yes. LYRES is a valid Wordle word.

It is not on the Wordle answer list, so it is unlikely to be a daily answer.

Plurals ending in S are almost never chosen as Wordle answers.

What does LYRES mean?

An ancient stringed musical instrument (a yoke lute chordophone) of Greek origin, consisting of two arms extending from a body to a crossbar (a yoke), and strings, parallel to the soundboard, connecting the body to the yoke.
A lyre-shaped sheet music holder that attaches to a wind instrument when a music stand is impractical.
A composer of lyric poetry.

Definition from Wiktionary, available under the CC BY-SA license.

Starter word rating: GoodIn the top 6% of all valid Wordle words for testing common letters.
Vowels: E
Unique letters: 5 of 5
Common letters: L, R, E

Hard-mode trap: 7 valid words fit the pattern _YRES. If you reach it, you may need several guesses to find the last letter.

Letter ratings use how often each letter appears in Wordle answers.

Tap its tiles to the colours Wordle showed, and the Wordle Solver lists every word that still fits, with the best next guess.