Is NODES a Wordle Word?

Yes. NODES is a valid Wordle word.

It is not on the Wordle answer list, so it is unlikely to be a daily answer.

Plurals ending in S are almost never chosen as Wordle answers.

What does NODES mean?

A knot, knob, protuberance or swelling.
The point where the orbit of a planet, as viewed from the Sun, intersects the ecliptic. The ascending and descending nodes refer respectively to the points where the planet moves from South to North and N to S; their respective symbols are ☊ and ☋.
A leaf node.

10 more noun definitions

A computer or other device attached to a network.
The point at which the lines of a funicular machine meet from different angular directions; — called also knot.
The point at which a curve crosses itself, being a double point of the curve. See crunode and acnode.
A similar point on a surface, where there is more than one tangent-plane.
A vertex or a leaf in a graph of a network, or other element in a data structure.
A hard concretion or incrustation which forms upon bones attacked with rheumatism, gout, or syphilis; sometimes also, a swelling in the neighborhood of a joint.
A point along a standing wave where the wave has minimal amplitude.
The knot, intrigue, or plot of a dramatic work.
A hole in the gnomon of a sundial, through which passes the ray of light which marks the hour of the day, the parallels of the Sun's declination, his place in the ecliptic, etc.
The word of interest in a KWIC, surrounded by left and right cotexts.

Definition from Wiktionary, available under the CC BY-SA license.

Starter word rating: AverageIn the top 17% of all valid Wordle words for testing common letters.
Vowels: O, E
Unique letters: 5 of 5
Common letters: O, E

Hard-mode trap: 9 valid words fit the pattern NO_ES. If you reach it, you may need several guesses to find the last letter.

Letter ratings use how often each letter appears in Wordle answers.

Tap its tiles to the colours Wordle showed, and the Wordle Solver lists every word that still fits, with the best next guess.