Is PYXES a Wordle Word?

Yes. PYXES is a valid Wordle word.

It is not on the Wordle answer list, so it is unlikely to be a daily answer.

Plurals ending in S are almost never chosen as Wordle answers.

What does PYXES mean?

A small, usually round container used to hold the consecrated bread of the Eucharist, especially used to bring communion to the sick, or others who are unable to attend Mass.
A box used in the British mint as a place of deposit for certain sample coins taken for a trial of the weight and fineness of metal before it is sent from the mint.
The box in which the compass is suspended; the binnacle.

1 more noun definition

Definition from Wiktionary, available under the CC BY-SA license.

Starter word rating: WeakIn the top 69% of all valid Wordle words for testing common letters.
Vowels: E
Unique letters: 5 of 5
Common letters: E
Rare letters: X

Letter ratings use how often each letter appears in Wordle answers.

Tap its tiles to the colours Wordle showed, and the Wordle Solver lists every word that still fits, with the best next guess.